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Can you take different anti depressants? Like an SSRI and a SSNRI?

Can you take different anti depressants? Like an SSRI and a SSNRI? Topic: Can you take different anti depressants? Like an SSRI and a SSNRI?
June 20, 2019 / By Leolin
Question: I am taking an SSRI Lexapro, but I still think I could feel better.Dr upped it to 2 10mgs at night, but a month later, it's okay, but I wonder if taking an SSNRI, like Wellbutrin, might help. Anyone been on both, or before I as the dr, do ya know if it would be safe?
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Best Answers: Can you take different anti depressants? Like an SSRI and a SSNRI?

Jalen Jalen | 5 days ago
I take Wellbutrin SR (150 mg) in the morning, and Lexapro (10 mg) in the evening, for depression and anxiety. I've been taking that for over a year and a half, and it's working very well for me. The Wellbutrin SR seems to help me to be more active - and wanting to do things - while the Lexapro makes me more mellow, and it helps me sleep better, too. They work on different areas of the brain, and kind of compliment each other. The last time I was in the doctor office, I had lost 8 lbs - not a lot, but in the right direction. I give the Wellbutrin SR the credit for the weight loss, since it does help me to be more active. Best of Luck to you :-) Paul.
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Jalen Originally Answered: Can you take different anti depressants? Like an SSRI and a SSNRI?
I take Wellbutrin SR (150 mg) in the morning, and Lexapro (10 mg) in the evening, for depression and anxiety. I've been taking that for over a year and a half, and it's working very well for me. The Wellbutrin SR seems to help me to be more active - and wanting to do things - while the Lexapro makes me more mellow, and it helps me sleep better, too. They work on different areas of the brain, and kind of compliment each other. The last time I was in the doctor office, I had lost 8 lbs - not a lot, but in the right direction. I give the Wellbutrin SR the credit for the weight loss, since it does help me to be more active. Best of Luck to you :-) Paul.

Ford Ford
Yes you can. Actually wellbutrin is not an ssnri, but anyway, the only concern is to not push the doses too high, because there is a somewhat rare condition called serotonin syndrome that you can get if your brain has too much serotonin. It can kill you by sending your body into shock and raising your body temperature to a dangerous level. I personally take 10mg of Lexapro and 150mg of Effexor at the same time, but it was a last resort type of thing because I keep trying to kill myself and ECT/Therapy wasn't working.
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Davie Davie
Wellbutrin's not an SSNRI. You can take it at the same time as Lexapro. I took Wellbutrin at the same time as Cymbalta for awhile.
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Balthasar Balthasar
I'm pretty sure you can take more than one antidepressant at a time. The best thing to do is to ask your doctor. S/he might add in another medication, or perhaps wean you off the Lexapro and try something else.
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Balthasar Originally Answered: Are my anti-depressants causing my rapid weight gain?
Experts say that for up to 25% of people, most antidepressant medications -- including the popular SSRI (selective serotonin reuptake inhibitor) drugs like Prozac, Lexapro, Paxil, and Zoloft -- can cause a weight gain of 10 pounds or more. "This is a phenomenon that was first noticed years ago when Prozac first came on the market. It didn't initially show up in the clinical trials because most of them were eight to 12 weeks in length, and the weight gain generally occurs with longer use. But it's definitely one of the side effects of this and other antidepressant medications. Although there are a number of theories as to why antidepressants lead to weight gain, Scientists believe that both appetite and metabolism may be affected. This is clearly a problem for the majority of drugs used to treat depression, and while it doesn't occur with every drug or for every person, when it does happen, it can be a significant problem that you shouldn't just ignore. Good luck!

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